Structural Biology Interest Group

Welcome to the homepage for the MSU Structural Biology Interest Group (SBIG)! This page contains information about our current meeting schedule and locations. Everyone is welcome at the meetings, but if you would like to receive emails, or if you would like to be included in the presentation schedule, please contact Dr. Fitzkee at nfitzkee @ (remove spaces).

Currently, SBIG meets at noon on the second Wednesday of each month in the chemistry conference room, Hand Lab 1135 (click here for a map). Occasionally, we meet elsewhere, so please double-check the announcements below for more details.

SBIG Meeting - 12/11

We will have SBIG this Wednesday 12/11 at 12:00 pm in the Chemistry Conference Room (Hand Lab 1135). It's a busy time, but we hope you'll join us for our final SBIG before the holidays.

Our speakers this week are:

  • Orr Bennett (Emerson Lab) - Orr will speak on protein phase diagrams; the paper for this presentation is here. Contact Nick Fitzkee if you would like the PDF.
  • Dr. Venkata Machha (Lewis Lab) - Venkata will present on SDS page and blotting methods.

See you Wednesday!


SBIG Meeting - 11/13

Once again, we'll have SBIG in the Chemistry Conference room at noon on Wednesday. We'll hear a presentation by David Wilson (Emerson Lab) on column cleaning and regeneration, and we will have a special guest from the Toghiani lab present on the use of statistics in chemistry. We hope to see you there!


SBIG Meeting - 9/11

At the Structual Biology Interest Group meeting last July, we decided to restructure things a bit. We are now meeting on the second Wednesday of each month at 12 pm (still in Hand Lab 1135). Instead of doing two research talks, we will have one research talk (20-30 minutes) and one talk that focuses on a protocol or recent paper (15-20 minutes). As always, we invite anyone with an interest in structural biology and molecular biophysics, regardless of background.

Our next meeting will be next Wednesday, Sept 11 (12 pm in Hand 1135). To kick off the new semester, pizza and soda will be provided. Dr. Joe Emerson will be speaking on some of his research into metal binding proteins, and Whitnee Simmons will be presenting a brief discussion of protein purification strategies.

See you next week!


SBIG Meeting - 7/12/2013

The Structural Biology Interest Group meets this Friday at noon in the Chemistry Conference Room (Hand Lab 1135). To encourage participation, free pizza and drinks will be provided at this meeting. In addition to the normal student presentations, we're going to discuss a few organizational items. There's no such thing as a free lunch, so when you come, please bring your ideas on the following topics:
  • Participation from members outside the Chemistry department has been low. One of the main goals of this group is to appeal to biological/medical research groups campus-wide. It has been suggested that changing the meeting day would help with this, and rotating the location may also be helpful. Our next meeting will be in September, so please come prepared to suggest days that may be more convenient.
  • Similarly, if there are any suggestions on topic or format changes, we should discuss those. One idea is to make the talks more selective by having student participants apply to present. Another idea is to reduce the number of talks to one per session, so that the entire meeting could more easily fit in a standard lunch break. It may also be helpful to invite on campus speakers to talk about jobs, applying for postdocs, etc.
  • Finally, there may be other faculty members or research groups who may be interested in the group. We will discuss possible outreach strategies that may help spread interest in our meetings.
If you have ideas about these topics (or anything else pertaining to the group), you can also email me at nfitzkee (at) with your thoughts. The presenters this week are both from the Fitzkee Lab. Ailin Wang will talk on her research, "Monitoring the Protein Dynamics during Binding to Gold Nanoparticles by Hydrogen/Deuterium Exchange." SriRamya Tata will present a talk on Allosteric Inhibition of HIV Integrase. Hope to see you there!

SBIG Meeting - 6/14/2013

The Structural Biology Interest Group meets this Friday at noon in the Chemistry Conference Room (Hand Lab 1135). This week we have two presenters from the Lewis lab. Venkata Machha will present the following paper:

"Energetic Basis of Uncoupling Folding from Binding for an Intrinsically Disordered Protein"
Drobnak, I. et al. (2013) JACS. 135 (4): 1288-1294. (link)

His colleague, Vu Le, will present this paper:

"The Role of DNA Shape in Protein-DNA Recognition."
Rohs, R. et al. (2009) Nat. Struct. Mol. Biol. 461: 1248-1253. (link)

Both of these papers are relatively short and look to be very interesting. I hope we'll see you there!



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